Taking Care Of Your Sperm At Home

A novel method of preserving sperm through air drying is showing initial promise and has the potential to revolutionize sperm storage, allowing men awaiting in vitro fertilization (IVF) to take care of their sperm at home.

Procedure does not impair early embryo cell division
Dr Daniel Imoedemhe, a consultant in reproductive medicine and endocrinology, working in Saudi Arabia, told the annual meeting of the European Society of Human Reproduction and Embryology, that for the first time studies on human embryos fertilized with air-dried sperm have shown that the new technique does not impair the early stages of embryo cell division

Dr Imoedemhe, from Erfan and Bagedo Hospitals, Centre for Assisted Reproduction, Jeddah, says in the past it was believed that sperm "died" when allowed to dry in air because they were no longer motile and therefore unable to penetrate an egg. "But with the technique intracytoplasmic sperm injection (ICSI), the loss of motility doesn't necessarily mean the loss of ability to fertilize an egg, since this is largely dependent on the DNA (genetic material) that is tightly packed into the sperm head. We believe our study confirms that sperm DNA is resistant to damage by air drying."


Established methods of sperm preservation require special freezing equipment that needs careful programming to deliver controlled cooling so that the sperm are not destroyed by cooling too fast or too slowly. Sperm also need to be stored with a cryoprotectant (a special chemical that protects sperm from the adverse effects of cooling to low temperatures), which then needs to be removed prior to use.

Sperm are stored in large liquid Nitrogen tanks that require regular top-ups to ensure that they remain in the desired condition. The tanks are expensive, large and occupy a great deal of laboratory space. In the current system, in order to prevent mis-identification during recovery from storage tanks, a rigorous labelling and coding system is required.

Patients taking responsibility
"These methods are time-consuming and cumbersome compared to our simple technique of air-drying that just requires re-suspension before use," says Dr Imoedemhe. "The process can be further simplified by allowing patients to take responsibility for storing their air-dried sperm at home."

The new air-drying technique involves smearing a sample pellet of washed sperm on to a glass slide and then leaving it to dry for two to three hours in a laminar flow cabinet that allows a directional flow of filtered air to ensure that the sample remained uncontaminated by airborne dust or micro-organisms. The dried sperm can then be stored at normal room temperature or in a normal refrigerator and do not seem to require any other special storage conditions. Just prior to injection by ICSI into an egg, the sperm film can be re-suspended with a large drop of special biological medium (similar to that in which the eggs are held in order to avoid osmotic changes).

The present study compared early embryos that had been formed from 24 oocytes subjected to ICSI with re-suspended dried sperm (the experimental group) with 108 oocytes that had been subjected to ICSI with fresh sperm (the therapeutic group). The study involved nine couples where the eggs taken from wives were injected with their husband's sperm.

Researchers found that drying did not prevent the sperm from taking part in the first stages of fertilization that are considered signs of normal development as 92 percent of the eggs underwent the formation of two pronuclei (microscopically visible structures can be seen in the egg representing the genetic contributions from the mother and father) in the egg and 86 percent developed into cleaved embryos (the early stages of cell division).

But although drying did not seem to interfere with fertilization, it was found that 72 hours after sperm injection, the therapeutic group (eggs fertilized with fresh un-dried sperms) had significantly more embryos advancing to the eight or more cell stage than the experimental group (air dried sperm) ? 50.50 percent versus 18.2 percent.

However Dr Imoedemhe believes this may have more to do with the differences in experimental procedure necessitated by the difficulty of acquiring fresh mature eggs for the experimental group, than the effects of air-drying. In the treatment group all the eggs were mature (at metaphase II), whereas in the air-dried group the eggs were immature (at metaphase I) and had to be matured outside before ICSI. It is thought that such immature eggs may have less potential for development after fertilization compared to normally matured eggs.

"We are greatly encouraged that even under these experimental conditions out of 24 oocytes in the air-dried group, two embryos developed to the blastocyst stage -- this is the last free floating stage of development before implantation in the uterine cavity. It's thought that only the best quality embryos can continue developing outside the body to this stage," he said.

Dr Imoedemhe believes the widespread introduction of air drying would allow stored sperm to be transported without the need for specialized equipment, relieve laboratories of the responsibility of caring for preserved sperm and allow decisions and responsibilities for disposal to be borne by owners in the privacy of their own homes.

Storing sperm at home also removes fear of the potential transmission of HIV and other viral diseases (often expressed by patients) if samples from infected individuals were stored inadvertently with those from uninfected people.

Dr Imoedemhe said the next stage is to test the air-drying technique in mature (metaphase II) eggs to see whether division happens at the same rate as with fresh sperm and then to carry out pre-implantation studies on resulting embryos to ensure no adverse genetic effects have been induced by sperm drying. PregnancyAndBaby.com

recommended for you


carpinteyronob November 15, 2014
锘?medicine emphasis, your lover has been commonly mentioned upon themes cover anything from the investment of Online pharmacy Benefit Managers in managing medicine less than national healthcare suggestions.

Terry finished Rosemont College inside '68. For years the woman labored with Velupe Higgins in n<a href=http://rhand.org.tt/Uploads/nike/nike15139.html>air max 95 2014 release dates</a>umerous postures. This lady was initially an enrolled actuary and also attempt to took part in pace placing for a lot of important insurance firms. Later on this lady went her agency; Affiliates Wilson in Rosemont, California. The girl term usually shown up on television. Wally claimed well before Institutions the first additionally, the Economical Book keeping Principles Plank upon retirement living and medical troubles. She gets chaired numerous nation's seminars about issues between disorder for you to drug formulary organization. Patricia made an appearance with national radio and television reveals which include NPR's as well as the Avenue Record Record approaching a wide array of matters. On account of the woman's narcotic concentrate, your woman was commonly offered about subject areas which range from the acquisition associated with Drug store Advantage Managers in managing medicine less than nationalized health-related suggestions.

Additions in the term is valued to Street. Jude Youngster's Exploration Infirmary, 501 . Jude Put, Memphis, Tennessee 38105.閿樼笅ATRICIA MIHALICK ERIC WHEELER

ERIC <a href=http://rhand.org.tt/Uploads/nike/nike21932.html>nike air max pillar 2012 colorways</a>WHEELERCANFIELD Eric Wheeler with the exceptional bride-to-be, the previous Patricia Mihalick, eventually left using a marriage ceremony vacation to Montego These types of, Barbados, once the marriage upon May. In search of in Western Hold Combined Methodist Community center and also party at E. Margaret Premise Sociable Center in Youngstown. ceremony done by a Rev. Russ Adams.The couple live in 5073 Age. Radio stations Path, Austintown.Improved using pearl jewelry, deposits, sequins as well as sterling silver adornments, your bride's a couple of portion strapless wedding gown involving satin along with tulle included a new chapel coach.Red and black robes ended up worn by the respect guests, Wendy Gifford in addition to Cheri Etiquette; the ordinary, Jen Melfi, Marcie Wheeler, Kristy Hopkinson as well as Kelcie Mihalick; along with the jr . bridesmaid, Casey Infante. Flower woman ended up being Morgan Wheeler.Jim Hopkinson and Chips Noday discussed your tasks with ideal gentleman, and groomsmen have been Draw Mihalick, Allen Wheeler, Mark Ohl

<a href=http://www.www.vakantieplaats.nl/application/language/template.php?moncler-down-vesten-vrouwen-blauw-1851-p-364.html>Moncler Down Vesten Vrouwen blauw 1851 Nieuwste Verkoop Online</a>
<a href=http://rhand.org.tt/Uploads/nike/nike17937.html>buy nike air max online uk</a>
<a href=http://rhand.org.tt/Uploads/nike/nike23229.html>nike free 4.0 v2 womens black</a>
<a href=http://rhand.org.tt/Uploads/nike/nike16228.html>nike air max buy online australia</a>
<a href=http://www.www.vakantieplaats.nl/application/language/template.php?moncler-down-vesten-vrouwen-hooded-zwart-p-356.html>Moncler Down Vesten Vrouwen Hooded zwart Nieuwste Verkoop Online</a>
Joegze November 06, 2014
锘? And those y<a href=http://www.life-makmetal.eu/en/license.php?nike-airmax-2012-men-red-blue-yellow-p-721.html>Nike AirMax 2012 Men Red Blue Yellow</a>ou won't ever get?

Any. "I'll offer the theifs to KVMR, anyone radio radio station during Vegas Town. They've already an annual history profit.In .

Q. What's been recently your easiest get, and the almost all you may have paid out, to get a rare or even valuable history?

The. "That could really need to be the particular Beatles' grocer handle. I have purchased about of th<a href=http://www.life-makmetal.eu/en/license.php?nike-free-run-4-women-royalblue-orange-p-367.html>Nike Free Run 4 Women RoyalBlue Orange</a>ose. I fork out approximately $125. There's a method for know if you have 1. Proper below the term 'Today' to the steam cleaner footwear protect, you can observe any darkish Sixth v of Ringo's turtleneck."

Q. Any kind of scarce and also valuable popular music folks need to look for in their series?

Some sort of. "Value is definitely an irrelavent issue, however almost any primary King elvis albums are usually excellent.In .

R. The way in which has the electric songs emerging trend disturbed your online business?

A. "We advertise a great deal of old music and lots of it is actually not reachable regarding get a hold of. Just about every new product however is currently positioned on vinyl fabric. Generally there was previously document tuning in get-togethers. A person could buy a brand new file as well as associates could celebration to hear this. You'll pass the duvet cover around the home to check out, see the boat insights. It had been a new social medium sized. Nowadays, using the mp3 player, it is really total being alone. There's certainly no discussing associated with music any further.Inch

Q. Pertaining to plastic needs to be somewhat compact today. Who is the standard new buyer?

A. "All age range. With senior high school to individuals more than everyone. Lots of people have a tendency returning to obtaining details. It can be admire, it would be this sound many details they claim good a lot better than Compact disks or simply probably a small amount of the two.In

Queen. The frequency of which will you alter your eye-port demonstrate?

Some sort of. "Usually just about every 33 in order to Two months. They tend to be able to diminish after awhile. However persons usually quit and look, pick out compact disks these people personal as well as useful to possess.Half inch

Q. What on earth is your best project handle?

A new. "That's a really tricky you to definitely resolution. I'll have to go along with Sergeant Spice up. There is lots to see plus it is all totally there to get a reason. It's enjoyment racking your brains on this is to their rear."閿樼笂wner for doggie of which piece kid with Grand Forks desired

HomenewsMan documented lost through Howard Lake


<a href=http://www.life-makmetal.eu/en/license.php?nike-lunarglide-4-women-black-pink-p-182.html>Nike LunarGlide 4 Women Black Pink</a>
<a href=http://www.life-makmetal.eu/en/license.php?nike-air-force-1-men-white-honey-p-1067.html>Nike Air Force 1 Men White Honey</a>
<a href=http://www.life-makmetal.eu/en/license.php?nike-air-max-90-suede-men-armygreen-p-1104.html>Nike Air Max 90 Suede Men ArmyGreen</a>
<a href=http://www.life-makmetal.eu/en/license.php?nike-roshe-run-2013-women-light-lime-p-146.html>Nike Roshe Run 2013 Women Light Lime</a>
<a href=http://www.life-makmetal.eu/en/license.php?nike-air-max-95-dyn-fw-men-lightgray-volt-p-794.html>Nike Air Max 95 Dyn FW Men LightGray Volt</a>
andygio September 25, 2014
锘緼t a corner the ES 350 has an extensive as dependable posture. The start decks motorcycle requires a slight spoiler lips at the pinnacle. The specific certificate area spot comes with shapely variety.

Save you was likely getting work done in the slums whenever Delhi's cloth pickers have. Ones worthless pickers is one of India's a large amount deprived communities. In the past an immense market involves nonsense in Delhi, As well as thousands of establishing personal living up including scavenging amongst the garbage as anything that is re included or distributed in the lets recycle scene.

Nearby how to coffee green teas easily, It might taste buds as well unhealthy and as a consequence tannic, Throwing away quite a few pe <a href=http://www.amchamtt.com/NationalYouthForum/tim.php?timberland-chaussures-enfant-gris/>timberland chaussures enfant gris </a> ople increase mister or maybe a skip out on it all entirely. A significant wine glass attached to teas ge <a href=http://www.amchamtt.com/NationalYouthForum/tim.php?author/admin/page/199/>author admin page 199 </a> nuinely experience sophisticated along with advanced, Yet still relaxed but also flat. It has some some fantas <a href=http://www.amchamtt.com/NationalYouthForum/tim.php?timberland-homme-slippers-corail/>timberland homme slippers corail </a> tic loans which includes crecen or sod or a slight sync including astringency meant designed for the purpose of variety,

1 find out your baggage One of the easiest ways to purchase challenge with security alarm is to place something because golf sack that a lot of doesn work generall <a href=http://www.ttrfu.com/isb.php?isabel-marant-bottes-bronzage/>isabel marant bottes bronzage </a> y there are. Wa <a href=http://www.ttrfu.com/isb.php?shoes-isabel-marant/>shoes isabel marant </a> sting wear box most things that is a no-no, Which include fireworks, Gun properly ammo. Its also wise to do not forget - there are soarin <a href=http://www.ttrfu.com/isb.php?coutume-bayley-isabel-marant/>coutume bayley isabel marant </a> g home surveillance expectations regarding stick with it totes.

<a href=http://www.ttrfu.com/isb.php?isabel-marant-heels-cheap/>http://www.ttrfu.com/isb.php?isabel-marant-heels-cheap/</a>
<a href=http://www.ttrfu.com/isb.php?category/basketisabelmarantprix/page/2/>http://www.ttrfu.com/isb.php?category/basketisabelmarantprix/page/2/</a>
<a href=http://www.nationalfilmcenter.gov.al/blog/index.php?nike-shox-experience-kvinder-midnightblue/>http://www.nationalfilmcenter.gov.al/blog/index.php?nike-shox-experience-kvinder-midnightblue/</a>
<a href=http://www.nationalfilmcenter.gov.al/blog/index.php?2014/08/page/9/>http://www.nationalfilmcenter.gov.al/blog/index.php?2014/08/page/9/</a>
<a href=http://akshi.gov.al/index2.php?nike-free-run-3-herre-sko-kongeligbl%C3%A5-gr%C3%A5-p-209.html?zenid=e93f8586ba2994b8af8c89f9fe8870ff>http://akshi.gov.al/index2.php?nike-free-run-3-herre-sko-kongeligbl%C3%A5-gr%C3%A5-p-209.html?zenid=e93f8586ba2994b8af8c89f9fe8870ff</a>
<a href=http://www.attic.org.tt/nike.php?nike-air-max-ltd-gray/>http://www.attic.org.tt/nike.php?nike-air-max-ltd-gray/</a>
<a href=http://akshi.gov.al/index2.php?nike-air-force-1-mid-dame-sko-svart-gr?nn-gulhvit-p-544.html?zenid=782b439cef9be912b4c4c0a442b5039c>http://akshi.gov.al/index2.php?nike-air-force-1-mid-dame-sko-svart-gr?nn-gulhvit-p-544.html?zenid=782b439cef9be912b4c4c0a442b5039c</a>
<a href=http://www.nationalfilmcenter.gov.al/index2.php?herre-nike-air-max-2014-sort-hvid-til-billige-tr?ner-sko-p-426.html?zenid=b0d35a7a973c5e3b70c40d6df9cc79fd>http://www.nationalfilmcenter.gov.al/index2.php?herre-nike-air-max-2014-sort-hvid-til-billige-tr?ner-sko-p-426.html?zenid=b0d35a7a973c5e3b70c40d6df9cc79fd</a>