Two studies presented today (Tuesday 21 June 2005) at the 21st annual conference of the European Society of Human Reproduction and Embryology provide further proof that single embryo transfer (SET) produces babies that are healthier than those born after multiple implantations.

Dr. Diane De Neubourg, from the Centre for Reproductive Medicine, Antwerp, Belgium, told the conference that babies born after (SET) are as healthy as singleton babies born after a spontaneous conception. She said that these findings, from the first well-documented follow- up of SET outcomes, further underlined the principle that SET was good clinical practice in IVF and ICSI.

Dr. De Neubourg and her team began by studying the outcomes of all SET pregnancies originating from IVF and ICSI at the Centre for Reproductive Medicine. In addition to analysing existing data, they sent questionnaires to all patients after birth or termination with questions about the pregnancy, delivery, and outcome of the children. These data were compared with data on spontaneously conceived singleton children from the Flemish register of perinatal epidemiology, which collects information from all Flemish obstetric units.

During the period, the overall percentage of SET as opposed to multiple embryo transfers was 33.2 percent The percentage of SET increased from 12.4 percent in 1998 to 53.8 percent in 2003, and the proportion of singleton pregnancies from IVF/ICSI from 66 percent in 1998 to 87 percent in 2003.

"We analysed the outcomes of the 251 SET pregnancies and births and found very little difference between the SET babies and those conceived naturally", said Dr. De Neubourg. "Birth weight was very similar, and so was gestational age. Stillbirth was also the same in both groups. The only significant difference we found was that SET pregnancies reported more hypertension (7.6% as opposed to 4.6). "We began this study because we wanted to investigate whether babies born after SET would have similarly poor obstetric outcomes to those reported from singleton births at the time when it was customary to transfer two or more embryos. We believe that our work shows clearly that SET is best both for mother and child. But we need to gain more data over a longer period of time. We intend to make a sub-analysis for different groups of patients and to further elucidate aspects of infertility and implantation."

Health economic aspects of ART are becoming increasingly important, said Dr. De Neubourg. "It is clear that more singletons who are healthy will cost less to society. In Belgium this understanding has resulted in laboratory costs for IVF and ICSI being reimbursed under a strict embryo transfer policy to secure the prevention of multiple pregnancies."


In another presentation, Dr. Anja Pinborg, from the Fertility Clinic at the Rigshospitalet, University of Copenhagen, Denmark, told the conference that the major health risks for IVF singleton babies came from their being the surviving twin from a dual embryo transfer. She and her team studied data collected between 1995 and 2001 from 11 Danish fertility clinics to assess the number of born IVF singletons in which a spontaneous reduction ('vanishing twin') occurred during pregnancy.

The team looked at the obstetric and long term outcomes of these singletons, and examined whether a poorer outcome for the babies was linked to the gestational age at the time of the spontaneous reduction. "Of all the IVF singletons born", said Dr.Pinborg, "10.4% originated from a twin gestation in early pregnancy. We found a clear correlation between the incidence of neurological problems in these babies and the time of onset of spontaneous reduction ? the later in pregnancy the twin was lost the higher the risk of neurological problems in the survivor. Furthermore, the risk of child death within the period of follow-up was higher in the survivors of a vanishing twin than in those born from a single gestation."

Dr. Pinborg said that she considered that single embryo transfer (SET) should be recommended to women of less than 37 years of age with at least two high quality embryos available. "Perhaps the age criteria could be even higher ? that depends on future studies", she said. "We need to inform our patients that vanishing twins are a considerable risk factor in IVF twin pregnancies and a relatively common consequence of dual embryo transfer", she said.


recommended for you


carpinteyropgf November 08, 2014
锘縰stin by 50 Percent Abbott Wraps Up Effort Tour Throughout Austin, tx Thurs Bing Place Presents Shoppers An electronic Expedition Inside Organizations Austin, tx Works Z Activities Luck This Morning More Baby Bees Visiting for Main Tx Park systems APD Researches Questionable Fatality with Three Properties 1000s of Guru Alternative Champions Preparing to Mar Saturday Austin, texas Lady with Genetic Testing for Melanoma Threat Friday Along with Cousin Deeda 7/12/13 Bettie's Field Business: Hawaiian Blackberry mobile phones Evaluation 'Helmet of Justice' Can assist Hook Hit, Function Drivers Cancer of the prostate Overtreated throughout Central Colorado Allison Appointments Stepping Stone Classes throughout Around Good ole' Airborne Pilates Overpowering Dallas Allison Comes to visit Stepping Stone School during To the south Austin, texas Over 3,000 Present Tales For Abortion Limitations Cbs television studios Humor Hype Tour Strikes Austin texas Senate Abortion Payment Hearing, Professional Lifestyle Move Organized Mon Individual With Service Doggie Turned down Having access to Chair for economic council Fridays With Grand uncle John This Ecnomic Result Connected with Minimal Sea Degrees Cops Langsing Away September Final Sunday Occurrence Jack-knife Accident Nevertheless Absolutely no Driver Determined Bettie'<a href=>Nike Air Max 95 DYN FW Men Blue Orange</a>s Field Place of work: Any Main Ranger Evaluation Retaining Secure During Drinking water In The Summer Comings in addition to Goings August Three or more, The year 2013 Colorado front range Home Board Steps Abo<a href=>Nike Air Max 2014 Men DarkBlue Pink</a>rtion Payment Frontward Texans Strike The Road The very best September Several Sunday No Word Place: Claims Enact Completely new Legal guidelines Person Hit Traversing Road 27 Dwelling To support Abortion Monthly bill Ability to hear Wednesday Mid-day Senate Sections Find out Paths, Young, small Proper rights Payments Fortin Cover Taking pictures Imagine To go in Plea If perhaps Internet business Ideas Seaworld Wildlife Ask Individuals To see This summer 4 Sunday Bettie's Package Company: White colored Household Lower Evaluation Georgetown Person Guides Some day Soon after Stylish Replacement unit Key Acevedo Weighs in at During Upon Migrants Problem Southerly Malay Adolescents Present Signs Of "Digital Dementia" Hit For that Treatment: Ufc To Battle Cancers of the breast Lower Enrollment with regard to Komen Austin tx Battle to your Remedy Austin tx Develops into Motor cyclist Paradise By using ROT Rally Savings account Empty<a href=>Men Nike Flyknit Trainer</a>ing Computer virus Hides With Fb No Written text Place: Feds Search for Technical Choice One-on-one along with Cyndi Lauper Tony adamowicz nomination Fridays Along with Big brother Fred 6/07/2013 Urban center Meters

<a href=>Nike Solarsoft Mule Slides Men Volt</a>
<a href=>Nike Free Run 4 Women Volt Blue</a>
<a href=>Nike Lunar Blazer Suede Women Pink White</a>
<a href=>Nike Free Run+ 2 Women Black Red</a>
<a href=>Nike Lunar Force 1 Fuse BHM Men Orange</a>