In a study conducted at Columbia University's Mailman School of Public Health and the New York Psychiatric Institute researchers found that increasing paternal age is significantly associated with increased rates of spontaneous abortion, a pregnancy loss occurring before twenty weeks of gestation.
August 2006 - Results indicate that as the male partner ages there is a steady increase in rate of miscarriage. Women with partners aged 35 or older had nearly three times as many miscarriages as compared with women conceiving with men younger than 25 years of age. This finding is independent of the woman's age and not explained by other factors such as diabetes, smoking, or previous spontaneous abortions, and adds to the growing realization of the importance of paternal characteristics for successful reproductive outcome.

"There has been a tremendous amount of research on women, and how their characteristics affect pregnancy outcomes. Of course, women's importance and centrality to pregnancy cannot be overstated. However, scientists seem to have forgotten that men are equal partners in reproduction, and their influence should be studied to the same degree. Our group has focused on men's influence on the health of their offspring, and we have made some fascinating discoveries," said Karine Kleinhaus, MD, MPH currently in Columbia's Department of Psychiatry and first author of the study. "This study shows how a man's age affects the likelihood of miscarriage."

Earlier research by the Columbia scientists showed that older men's wives suffer from preeclampsia, while the offspring of older men are more likely to get schizophrenia. "This is not as surprising as it may sound at first, as it was already shown by other researchers that older men have more abnormalities in their sperm, and that their children are more susceptible to certain birth defects," observes Dr. Klienhaus. In fact, the American Society for Reproductive Medicine has set an upper age limit of 40 years old for semen donors because of the increased risk of genetic abnormalities in the offspring of older fathers.

The international team of scientists involved in the study used a large historical data set containing information on many characteristics of mothers and fathers that might contribute to spontaneous abortion. The researchers analyzed data from the ante-natal or post-partum interviews of 13,865 women. This data was recorded in the Jerusalem Perinatal Study, a population-based cohort derived from 92,408 births in Jerusalem in 1964-1976.

Accordingly, the study, which focused exclusively on spontaneous abortion as the outcome, has as one of its strengths its large sample size and its extensive data, which permit consideration of important potential confounders not included together in other analyses. These include variables such as maternal diabetes, parity, history of prior spontaneous and induced abortions, and history of maternal smoking, and socioeconomic status.

The cohort used for this study is unique, with immigrants from many origins, including Iran, Iraq, Afghanistan and countries of North Africa, as well as Central and Eastern Europe. "This broad mix of backgrounds makes our study findings more generalizable," observed Susan Harlap, MD, professor of clinical epidemiology in the Mailman School of Public Health's Department of Epidemiology, and the leader of this research team. "While several previous studies suggested that father's age might contribute to miscarriage, they failed to clarify whether there is a cut-off age or a progressive trend over the whole range of ages."

The study findings generate strong support for the association of increasing paternal age with increasing rates of spontaneous abortion, and are corroborated by other published studies. "Advanced paternal age may result in only a slight increase in the chance of spontaneous abortion for a specific couple. Nevertheless, as child bearing is increasingly delayed in Western societies, this study provides important information for people who are planning their families," said Dr. Kleinhaus. "The study also adds to a growing understanding of how men's age, health, and occupations can affect their partner's pregnancies and the offspring's future development."

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Guilford Area, NC A sheriff's deputy when using the Guilford County Sheriff's Place of work had been in pain throughout a Driving under the influence police arrest in Greensboro past due Thursday night.

MCpl. Stokes imprisoned Amy Jr . Patterson about I actually 40/85 within the Southern Sony ericsson elm Streets area for your Driving while intoxicated impose as well as located him within his cruiser motorbike right well before night time, in accordance with the sheriff's company. The driver of someone else automobile strike the rear of Stokes's easy riding bike within the directors edge.

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Deputies mentioned the motive force, Jessica Nobles Blackstock, together with the girl's individual had been taken up a healthcare facility along with Stokes and Patterson regarding insignificant injury.

Patterson seemed to be convicted of Driving under the influence, Opened Package, Racing in addition to Inability to help keep Road regarding Take a trip by the sheriff's workplace. Blackstock appeared to be faced with a Disappointment to advance Over in addition to Breakdown to lessen pace because of the Greensboro Law enforcement Team.

Deputy Stokes will be property dealing with his or her incidents.

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h to them,In . said O'Neill Stephens.

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Florida's perfect Medicaid choice may be to leave this course totally.

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"Florida is a great idea to consider" going out, proclaimed Edmund Haislmaier, elderly study other within the practical Tradition Base. He or she rates in which 40 reports would come released ahead of time fiscally by just escaping period of time cash flow health care method.

The driving force regarding dumping State medicaid programs is the brand new fed health legislations, and that is scheduled in order to grow the swimming pool regarding qualified customers with 2014.

Beginning that will 12 months, Medicaid will certainly expand to incorporate you are not profits approximately 133 percentage of your national hardship stage, which can be $29,327 for the family of three truly.

Haislmaier claims that within expresses which fall Medicaid, your program's very low profits customers could in its place collect national subsidies to purchase personal insurance policy as a result of talk about geneva chamonix transfers, as well as a result of work during 2014.

Suggests looking beyond Low income health programs would likely become completely responsible for remaining State health programs clients who require assisted living as well as other long term caution, regarding premiums and various Medicaid expenditures with regard to Medicare insurance receivers.

Nevertheless Haislmaier says that would likely always be fabric increase designed for Sarasota simply because all others would likely go into the insurance protection swaps.

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Although Haislmaier cautions of which his computations are standard reports, reports throughout the country are generally really checking out the opt out solution.

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