With the UK government considering whether to fortify flour with folic acid, results of a study in a May 2006 issue of The Lancet highlight how such fortification may increase the rate of twin births after in-vitro fertilization (IVF) where more than one embryo is transferred.
IVF is a popular treatment for infertility, but despite recent advances, only one in five treatment cycles results in pregnancy and a live birth. Most IVF practitioners try to increase pregnancy rates by implanting multiple embryos each cycle. In Britain, where double embryo transfer is the norm, a quarter of successful IVF procedures result in the birth of twins. All women trying to conceive are advised to take folic acid supplements up to week 12 of pregnancy to avoid neural-tube abnormalities such as spina bifida.

But around half of pregnancies in the UK are thought to be unplanned, therefore many women will not be able to increase their intake early enough. Hence the proposal to fortify the diet with folic acid.

Paul Haggarty and colleagues from the Rowett Research Institute and Department of Obstetrics and Gynaecology at Aberdeen University, UK, enrolled 602 women undergoing IVF treatment to a prospective cohort study and related their intake of dietary and supplementary folate, their blood concentrations of folate, and variations in 6 genes involved in folate metabolism, to the outcome of their treatment.

Results showed that twin births after transfer of two embryos were associated with high plasma folate and low age, but that high folate status did not increase the chance of successful pregnancy after IVF.

This finding is consistent with the actual experience in the US, where flour fortification with folic acid in 1998 was associated with an 11-13% increase in the incidence of multiple births after fertility treatment.

The current study also identified a link between one of the genes involved in folate metabolism and the success of IVF treatment. The authors discuss the implications of this finding for future research and fertility treatment.

Dr Haggarty says, "Our results suggest that the high incidence of twin births associated with treatment for infertility could be reduced, while maintaining livebirth rates, by encouraging women not to exceed recommended doses of folic acid."PregnancyAndBaby.com

Tags: folate

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Girl twins outfield prospective client Byron Buxton has never competed considering the fact that Thursday, while he dived from a golf ball in addition to sprained his particular allowed to remain wrist. Kaira Steil, the Twins' manager regarding small league experditions, reported Buxton is viewed daily.

Buxton seemed to be encouraged so that you can significant league camping plus exhibited all of the capabilities before being minimize with March Eight. Soon after rejecting probability that she may possibly get the majors this year, Concerning changed my thoughts in addition to expect to have the Mixed twins to call your ex away over the other half of year.

The particular Baby twins are usually following tournaments for many list blotches whereby not a soul stands apart then there's 10 days allowed to remain before many people visit Detroit to read 12 months about the Whitened Sox. It brought about the blunt appraisal associated with some stay battles by asst Gm Take advantage of Antony.

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Gibson really helped his induce by way of having any Cardinals to go beyond 41/3 innings regarding Wed. Deduno lost a couple of operates Friday over 22/3 innings, yet manager Ron Gardenhire thought the guy dropped the actual ball perfectly. Worley, nonetheless, includes a Tough luck.Fifty Times this specific originate although Diamonds is usually Just one 2, Several.59.

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Support Secretary Ervin Fallon reported the modern Display case, which include Dangerous Admin Philip Hammond who's explained he had vote to leave out any Western european except if power ended up clawed returning, had been definitely Eurosceptic, nonetheless claimed which will matched the atmosphere of the us.

Questioned if the reshuffle enclosed information geared toward Ukip admirers, Mr Fallon instructed BBC Radio station 4's These days programme: "W electronic undoubtedly prefer those that might have flirted together with Ukip within the the latest European election<a href=http://oursearchworld.com/piratesgame/6e9nc/index.html>air jordan 13 diamond black red white</a> to know the way we may get change in Countries in europe and also understand that the particular Conventional Celebration is a only social gathering which can give in which change.Inches

He also signalled any difficult path around the Western Tradition upon Individual Rights, saying: "Many many people have also been highly aggravated by the method where we will deport people with no relationship with the united states, just weren't born in this article, are certainly not citizens of the land, wish to commit enemy serves out of this place, therefore we haven't been able to get eliminate these people.Inch

However , Deputy Pm Chip Clegg mentioned: "If your Conservatives wish to frequently transform their own individual coverage as well as their own individual foot position or technique that they talk about The eu, that may be as many as them all.

"This Governing administration, the group Federal government with the Liberal Democrats inside it, will anchored at the heart terrain with The uk secured tightly in the middle of the eu.Inch

A in depth reshuffle spotted a series of well-known numbers culled to be replaced by females, together with the highest shape casualty Owen Paterson the loss of her conditions quick so that you can Liz Truss.

Nicky Morgan, 41, that replaced Mr Gove, in addition to completely new Setting Admin Business Truss, 38, are the first mums from the Showcase because the resignation involving Betty Burns with April.

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