Predicting Postpartum Depression Risk

Levels of a hormone may help moms-to-be and their care providers predict the chances she will develop postpartum depression before her baby is even born.

Sad depressed woman

Researchers have discovered that levels of a certain hormone released by the placenta may show a connection to Mom’s chances of developing postpartum depression. Measuring the hormone, called placental corticotropin-releasing hormone (pCRH), may one day help identify women most at risk and allow for care providers to intervene early.

Placenta clues

The levels of pCRH in a pregnant woman’s blood generally rise sharply before labor begins and is thought to play a part in the timing of delivery. Researchers in California measured the levels of pCRH in the blood of around 170 pregnant women at 15, 19, 25, 31 and 36 weeks. They then followed up with the moms at 3 and 6 months postpartum to assess for depression. They discovered that women with the highest amounts of pCRH at 25 weeks were found to have the highest rates of postpartum depression.

"Women who show high levels of this hormone prenatally are at increased risk," said study co-author Laura Glynn, a psychologist at Chapman University in California.

Postpartum depression

The baby blues are common after you have a baby -- your hormones are going wild and boo-hooing at the littlest thing is totally normal. Postpartum depression, however, is more intense. It can usually be identified by a number of symptoms, such as loss of appetite, intense irritability or anger, severe mood swings, inability to bond with your baby or withdrawal from family and friends.

Experts recommend contacting your doctor if symptoms don’t fade in two or so weeks, are getting worse, make it hard to care for yourself or your baby or include thoughts of harming yourself or your baby.

This hormone and how it relates to the mom’s chances of postpartum depression merits more study, but if there comes a time where chances of developing this type of depression can be detected before birth, it will really help moms, especially those who may not seek help or are afraid to.

More on your postpartum health

Postpartum changes and your body
Common questions about postpartum depression
Breaking the silence on prenatal depression


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Hollister April 09, 2014
MARTIN: You say he regarded non-violence as a tactic, Thank you but I cannot stay.But I'll sing you a little song You'll hear it as I fly along And you'll hear it long after I'm gone I'll sing you a little song (APPLAUSE) HARDING: Megan Reilly Her new album's very beautiful and it's called "The Well" It's time to let you stretch your legs and grab a cup of tea When we return from the break Will Sheff of Okkervil River and writer Colson Whitehead will have finally finished hair and makeup You've got to look your best after all when you're on NPR (APPLAUSE) HARDING: Welcome back I'm John Wesley Harding and this is THE CABINET OF WONDERS ON NPR where words music and comedy find peace love and understanding though they do occasionally find them a little funny As someone extremely forthright said when dissing the scribes of today I assure you I'd rather be quite dead than read what those hacks have to say When I said what about Colson Whitehead he conceded and shouted hooray Ladies and gentlemen Colson Whitehead (APPLAUSE) COLSON WHITEHEAD: How de do Saul Bellow once said that fiction is the higher biography In other words fiction is payback on those who have wronged you It took me a while for me to understand this lesson so instead of coming out with an autobiographical first novel I came out with an autobiographical fourth novel "Sag Harbor" In this section the protagonist is wrestling with the fact that New Coke has replaced Old Coke (LAUGHTER) WHITEHEAD: (Reading) I've been addicted to Coke to years with a two or three can-a-day habit since the fifth grade When my sister told me not to be so hyper or my parents told me to knock it off I vibrated with the strain of keeping still and wondered why nature had cursed me so It wasn't until I was in high school that I discovered what caffeine was (Reading) My love for Coke went beyond mere buzz however How could one not be charmed by the effervescent joviality of a tall glass of the stuff The manic activity of the bubbles popping reforming popping anew sliding up the inside of the glass to freedom as if the beverage were actually miraculously caffeinated on itself (Reading) That tart first sip preferably with ice knocking against the lips for an added sensory flourish that stunned the brain into total recall of pleasure of all the Cokes consumed before and all those impending Cokes the long line of satisfaction underpinning a life (Reading) What forgiveness for the supreme disappointment of a fountain Coke that had turned out to be fizz-less and dead Or a lukewarm Coke that had been sitting for a while falling away from its ideal temperature of 465 degrees Fahrenheit slash eight degrees Celsius All the bubbles fled so that it had become a useless mud of sugar which is what New Coke tasted like actually (Reading) I remember when I first heard they were changing the formula April 23 1985 Within days I had coined the local market on Old Coke in the grid defined by 106 Street to the north 96 to the south and from Amsterdam to the river buying up what I could from corner bodegas the increasingly slick delis popping up on Broadway and the assorted stationery stores of the Hood (Reading) By the time New coke started to appear I was well prepared with a huge stash in my closet a prayer against doomsday I had no dreams of profiteering of selling my stock at a dear price to aficionados when the day came that the people of earth discovered the treasure they had destroyed as if the Cola were an exquisite lizard or spiny bi-valve driven to extinction in our race's savage drive to ruin (Reading) No I wanted it all to myself like an art thief who steals nude descending a staircase or some key Picasso and hangs it on the wall of his own private gallery for his wicked and ingrown pleasure At peace with the fact that the world is unaware of his activities and perhaps that's actually the point of the entire exercise (Reading) When I'd finished scurrying up and down the avenues and hauling my six packs back to my lair it seemed as though I had enough Coke for a lifetime But of course it went fast I couldn't keep my hands off the stuff My parents had a party and my mother asked if she could borrow a few cans for mixers (Reading) Borrow How did she even know about my stash If she knew that what else did she know (LAUGHTER) WHITEHEAD: (Reading) How can I answer but with a yes What a horror it was to see all those half finished cans strewn around the house It was a battlefield Mine own Gettysburg And I learned that day what it is to mourn as I heard the sad exhausted hissing as I poured the remains down the sink Thank you (APPLAUSE) HARDING: Ladies and Gentlemen Colson Whitehead What a glamorous night of golden glitter You're glad you got a baby sitter Better than cleaning out Kitty Litter and staying at home and growing embittered Time to Twitter here's a bitter Dean and Britta (APPLAUSE) (SOUNDBITE OF SONG "I'LL KEEP IT WITH MINE") BRITTA PHILLIPS: (Singer) You can search babe at any cost But how long babe can you search for what's not lost Everybody will help you Some people are very kind But if I can save you any time Come on give it to me I'll keep it with mine (Singer) I can't help it if you might think I am odd If I say I don't love you But for what you're not Everybody will help you Discover what you set out to find But if I can save you any time Come on give it to me I'll keep it with mine (Singer) The train leaves at half past ten But it'll be back tomorrow same time again The conductor is still stuck on the line But if I can save you any time Come on give it to me I'll keep it with mine (APPLAUSE) HARDING: Dean and Britta Townsmen cast your eyes on Mirman (APPLAUSE) HARDING: No Australian Bruce or warlike German Of Russian stock this comic sir Like Yakov Smirnoff only funny-yer Eugene Mirman (APPLAUSE) MIRMAN: Wes. It is great to be here I get things delivered to a mailbox place on Fifth Avenue because I'm often not home and they sign Anyway not important What's important is whenever a package arrives the man from the store calls me and I pick up the phone and he just goes "You have a small package" (LAUGHTER) MIRMAN: And that's it I can't tell if he knows he's pranking me Look if he enjoys it and then weirdly depending on what I've ordered from Amazon he'll be like "You have a medium package" And I'm like "That's fine" I can never tell if he gets how awesome it is that his job is to call strangers and politely mock their ding-dong One thing that I very much do not like is when people on the street try to get money from me for a cause Like I'm not going to be like oh my God I'll give you $50 it sounds like the whales are very important And I get really mad because also there's like this assumption that I've done nothing helpful all week till they stopped me I was at a costume shop I was at Hollywood Adventure on 14th Street and I was walking downtown to a meeting and I had headphones on I was listening to headphones And this lady starts flagging me down like like clearly I can't hear so she's like waving like a ghost is tickling me and I don't like it And I take off my headphones and I look at her because that's what polite people do and she goes "Are you a fan of the earth" I did not like that question It made me so mad It made me just want to like set a whale on fire and not use it for heat What I bought at the costume shop was a tear stick It is like lipstick but it is menthol and you put it on your eyes and it burns your face and it makes you cry like a lot You think people are good actors No someone's blown menthol in their face No one's a very good actor So as she was like looking at me it was like "Are you a fan of the earth" I had taken the cap off and put menthol on my hand and went like this and I looked at her and as earnestly as I could I was just like "No not any more not since global warming" And then I just started crying She was so confused because I clearly believed in global warming but I thought it was something the earth did to people and it made me cry I joined the CSA I'm already helping the earth (APPLAUSE) MIRMAN: All right Goodnight HARDING: Eugene Mirman As for our next guest there's a limerick there's one limerick every show This is today's one There was once a man who was stone deaf Music was just notes on a clef But his cochlea's quivered to Okkervil river and now here he hears thanks to Will Sheff Ladies and gentlemen would you please welcome to the stage Will Sheff (APPLAUSE) WILL SHEFF: Here we go All right Excellent (SOUNDBITE OF SONG "A STONE") SHEFF: (Singing) Hot breath rough skin warm laughs and smiling The loveliest words whispered and meant you like all these things But though you like all these things You love a stone You love a stone Because it's smooth and it's cold (Singing) You love white veins You love hard grey The heaviest weight The clumsiest shape The earthiest smell And the hollowest tone You love a stone (Singing) And I'm found too fast called too fond of flames Then I'm phoning my friends Then I'm sharing the blame Cause you're pulling pebbles out of the drain miles ago And you're out singing songs while I'm down shouting names at the flickerless screen And I'm going insane Am I losing my cool Overstating my case Well sugar what can I say (Singing) You know I never claimed that I was a stone And you love a stone You love white veins you love hard grey the heaviest weight The clumsiest shape and the earthiest smell And the hollowest tone You love a stone (Singing) And it's you love a stone Because it's dark and it's old Well if it could start feeling alive you'd stop living alone You know I think I believe that if stones could dream they'd dream of being laid side-by-side piece-by-piece And turned into a castle for some towering queen They're unable to know (Singing) And when that queen's daughter came of age I believe she'd be lovely and stubborn and brave And suitors would journey from kingdoms away To make themselves known And I think that I know the bitter dismay of a lover who brought fresh bouquets every day And she turned him away To remember some knave who once gave just one rose And it was one day and that was years ago (APPLAUSE) SHEFF: Thank you guys Thank you so much Bringing David Naglar up I've known David for a while but this is the first time we've actually played together I'm really excited about it This is a song by a guy named David Ackles (SOUNDBITE OF SONG "BE MY FRIEND") SHEFF: (Singing) This world's a lonely place to walk around in This world's a place where life is hard to spend But we can help each other live Everyone can give the simple gift the words that lift "Be My Friend" (Singing) Some days you wake up feeling nothing but fear Some days you wonder why God put you here And all at once some little words what was that you heard Why someone said from Gilead "Be My Friend" (Singing) This world may not bring much comfort to you This world may lose its touch of kindness too And who's to blame Hell can't you see Only you and me So if I may I'd like to say "Be My Friend" (APPLAUSE) SHEFF: Thanks guys HARDING: Ladies and gentlemen that was Will Sheff It's getting hot in here but wait till Rick Moody and Carl Newman of the New Pornographers have graced this stage Breathe deep maybe take a knee bend It's all just ahead on THE CABINET OF WONDERS (APPLAUSE) HARDING: Hello again I'm John Wesley Harding This is THE CABINET OF WONDERS and the game's still on (APPLAUSE) HARDING: I've just been on tour in the south of your beautiful country with Joe Pernice and Rick Moody And Joe Pernice and I were listening in the front to a lot of the soft rock that we like a lot and we were listening particularly to Ned Dohini to Dean Friedman I think there was a little Steely Dan perhaps some Chicago I don't remember But after about two hours of this incredible listening experience I looked behind me to find that Rick Moody had actually slashed his wrists and was dead in the back of the car I tweeted this fact to the world at large and within half an hour I got a reply from Dean Friedman himself Writer of the hit song "Arial" And he said "I'm glad you're enjoying my music So sorry to hear about Rick Moody" Ladies and gentlemen of the jury judge ye not in haste or fury his written words are so appealing but what of his most private feelings Does he love you Does he hate you Moody by name or Moody by nature Ladies and gentlemen friend of the CABINET it's Mr Rick Moody (APPLAUSE) MOODY: Well I've got a new book out It's a collection of essays on music And there's a 75 page assault on the drum machine It's called "Europe Forsake Your Drum Machines" And this is how it starts (Reading) Drummers of Europe throw off your chains For too long now you've let the soot collect on your kits in the garage where you once kept a car Many have been the days when you have happened through there and seen the kit under its plastic sheet or moldy discolored blankets (Reading) Have you not wondered what it would sound like to be busy yourself on the skins Drummers of Europe is it ever the philosophy of your continent to say a thing is lost and then to yield to that loss as though it were a virtue as though nothing can be done to redress the situation (Reading) Drummers of Europe don't go on this way You might a-new at first timidly apply your sticks and your brushes to the cymbals and toms You might again attempt the impossible threes against fours (Reading) You might completely blow some maniacal fill as perfected on the recordings of jazz drummers of old You might again annoy neighbors and passers by until late into the night Drummers of Europe once there were jokes in profusion at your expense that you were always the least sophisticated member of the band (Reading) Your wife or your husband or your partner's told you that you are not a very good drummer That you have trouble keeping time That you are unable to avoid speeding up Drummers of Europe these things are no obstacle to what lies before you today The restoration of Europe to its greatness in the matter of indigenous musics (Reading) If by indigenous music we are understood to mean simply music that is primarily made by human beings in a particular place and time all attempting to play together (Reading) Drummers of Europe they will it is true eject you from the clubs where they have grown decadent and somehow satisfied by the sight of a pair of guys twitching over laptops They tolerate the predictable video projections on the jumbotron (Reading) But it is no matter if you are ejected from the raves It is no matter if that one irritating acquaintance the one with the really foul breath and meth teeth attempts to make you believe that your time drummers of Europe is gone (Reading) Drummers of Europe if it's necessary to be alone at first practicing on the mattresses with well worn sticks or un-rubberized practice pads then so be it Drummers of Europe even if you have sold the kit borrow a plastic paint container or a garbage can to serve as both kick drum and snare so be it drummers of Europe (Reading) Your inability is your mastery Your enthusiasm is all that's required Remember drummers of Europe the wind that blows north from the Sahara Remember the gypsies that moved across your plains Drummers of Europe look at your waves of immigration and consider how you are the greatest polyglot experiment (Reading) You are at the center of the world what with all the music that is part of your ensemble now the polyrhythm's of Africa the drones of Asian music the klesmer music of your missing Hebraic minority The reggae that's been exported back to you from former colonies (Reading) Drummers of Europe this is all your legacy All you have to do is take up your sticks That day job you have in your contracting economy should be no impediment Embrace your unprofessionalism You can't deny it You've never done anything in your life that's made you as happy as when you play Those days need not be in the past drummers of Europe (Reading) Those days may be at hand Drummers of Europe your time is now (APPLAUSE) MOODY: Adam Gold on the drums HARDING: Rick Moody welcome to his new direction And this next guest A joke that when I was 10 made me laugh I was going to buy you some pornography then I remembered you didn't have a pornograph Here's a pornographer who has both His songs are as sexy as Schuman's A truly remarkable human please welcome to the stage A C Newman (APPLAUSE) A C NEWMAN: We're going to do something brave We're going to do a song I've been working on currently I think it's going to be real psychedelic when it's done Let's try this (SOUNDBITE OF SONG) NEWMAN: (Singing) Who's gonna save yourself from yesterday I fan the flames Why save yourself while you expect the word self button push tidal blank You're gonna knock yourself out Knock yourself out (Singing) Roots in the ground provisional Visible you'll find to the naked eye Know what you love precise millions of bucks will check you out You can talk yourself down Talk yourself down (Singing) Da-da-da-da-da da-da Da-da-da-da-da Da-da-da-da-da da-da Da-da-da-da-da da-da Da-da-da-da-da da-da Na-ah-ah-aaaaaaaa Na-ah-ah-aaaaaaaa (Singing) You can get lost out here Lost out here You could get lost out here Lost out here (Singing) Went to the woods I know we should have planned We understand Because beseech ourselves said you'd be back no beaten track Could do what you choose But don't knock yourself out Don't knock yourself out (Singing) Da-da-da-da-da da-da Da-da-da-da-da Da-da-da-da-da da-da Da-da-da-da-da da-da Da-da-da-da-da da-da Na-ah-ah-aaaaaaaa Na-ah-ah-aaaaaaaa (Singing) You could get lost out here Lost out here You could get lost out here Lost out here You could get lost out here Lost out here (APPLAUSE) NEWMAN: Thank you This one's. this is a song I really love HARDING: What is this song NEWMAN: I learned it from Bryan Ferry but it's written by these guys named Gallagher and Lyle HARDING: How nice to have you back again Carl NEWMAN: Thanks HARDING: And congratulations on your baby NEWMAN: Thank you HARDING: Who is how old NEWMAN: He's nine weeks old HARDING: Nine weeks old (SOUNDBITE OF SONG "HEART ON MY SLEEVE") NEWMAN: (Singing) One two three four . I wear my heart on my sleeve I'm not afraid To say what I mean Mean what I say Step myself up Let myself down I may be a fool Spread it around But I I just want to let you know sometimes I find it so hard not to show So I sigh and try not to let my feelings show (Singing) I wear my heart on my sleeve Don't count the cost I can't read enough And surely I'm lost Find you get burned times you get bruised but it's my life I do as I choose And I just want to let you know sometimes I find it so hard not to show So I sigh baby you're not alone (Singing) I wear my heart on my sleeve I wear my heart on my sleeve I wear my heart on my sleeve I wear my heart on my sleeve (Singing) And I - I just want to let you know sometimes I find it so hard not to show So I sigh Baby you're not alone (Singing) I wear my heart n my sleeve Wear your heart on your sleeve I wear my heart on my sleeve Wear your heart on your sleeve Wear your heart on your sleeve Wear your heart on your sleeve Wear your heart on your sleeve Wear your heart on your sleeve (APPLAUSE) HARDING: Carl Newman Let's get everybody back on the stage now Our CABINET is now ended These are actors as I foretold you were all spirits and are melted into air thin air And like the baseless fabric of this Vivienne Westwood suit the brilliant songs the thought provoking readings the surly comics the great City Winery itself yay all which is inherits shall dissolve and like this insubstantial pageant faded leave not a guitar pick behind We are such stuff as dreams are made on and our little life is rounded with a sleep Ladies and gentlemen the CABINET is closed (APPLAUSE) HARDING: This is the song we like to finish with Thank you so much for coming this evening (SOUNDBITE OF SONG "SINGING A SONG IN THE MORNING") HARDING: (Singing) Singing a song in the morning singing it again at night I don't even know what I'm singing about but it makes feel I feel all right yeah yeah It makes me feel I feel all right (Singing) Singing a song in the morning Singing it again at night I don't even know what I'm singing about but it makes me feel I feel all right Come on Rick It makes me feel I feel all right. Copyright 2010 NPR All rights reserved No quotes from the materials contained herein may be used in any media without attribution to NPR This transcript is provided for personal noncommercial use only pursuant to our Terms of Use Any other use requires NPR's prior permission Visit our permissions page for further information NPR transcripts are created on a rush deadline by a contractor for NPR and accuracy and availability may vary This text may not be in its final form and may be updated or revised in the future Please be aware that the authoritative record of NPR's programming is the audio also know as Dean and Britta. recently wrote an in which she confessed to developing an allergy to that phrase. The seed and chemical company DuPont set up a with a question printed at the top in big, she attempted suicide for the third time and she remains in a Kansas City hospital. speaking with us from Maryville, "Those girls were abused," Abbott explains, But because of the environment.